Buffer composition, concentration, and freeze–thaw cycles probably matter as much as fridge time. I’m not sure how standardized the available stability datasets are across different reconstituted peptides, though.
that matters. storage time and temperature can change what’s actually available, so stability data is far more useful than assuming “fridge = forever.”
How quickly does stability actually drop for a given reconstituted peptide—days, weeks, or does it vary too much by sequence and formulation to generalize? I’m not sure fridge storage alone tells us much without the underlying stability data.
a fridge slows degradation; it doesn’t put peptides in suspended animation. that matters because “stored cold” isn’t the same as “still potent,” especially after repeated handling.
A fridge temperature alone doesn’t prove stability. Temperature swings, light exposure, and repeated freeze-thaw cycles may matter more than the label on the appliance, so the data has to match the actual formulation and handling.
Reconstituted peptides are more like leftovers than vampires: the fridge slows the clock, but it doesn’t stop it. “It’s been cold, so it’s immortal” is definitely not a stability protocol 😄
Discussion 21