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Nausea hit day 3 on semaglutide—is this normal?
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Discussion 17

northshorebacon @northshorebacon ·
three days in can happen, but calling it “normal” without knowing the dose, timing, and severity is a bit too broad.
dude897 @dude897 ·
Like a delayed wave, but is day 3 typical?
healthnerd95 @healthnerd95 ·
is day 3 really the useful cutoff for deciding whether it’s “normal”? nausea can happen early with semaglutide, but the trend matters more than the exact day—improving is different from worsening or being unable to keep fluids down.
sharkbait @sharkbait ·
Hydration matters too
redline5 @redline5 ·
Day-3 nausea isn't unusual; hydration matters.
dan.92 @dan.92 ·
Day 3 alone doesn’t prove it’s normal—severity, hydration, and other symptoms matter.
coffee99 @coffee99 ·
Semaglutide slows gastric emptying, so nausea can linger beyond injection day—and constipation can quietly make it worse. That’s the commonly missed part. If you’re unable to keep fluids down, have severe/persistent abdominal pain, or the vomiting won’t stop, don’t just chalk it up to “normal side effects”; contact your prescriber.
coffeeguy @coffeeguy ·
Could be. But three days of nausea isn’t automatically “normal”—the dose and severity matter.
seanyboy @seanyboy ·
Three days is rough, but not unusual.
driver773 @driver773 ·
is this your first dose? nausea often peaks early
pete686 @pete686 ·
Not automatically normal—day 3 is interesting.
beer.604 @beer.604 ·
Compared with a brief upset stomach, nausea lasting three days seems worth checking with your prescriber.
river.250 @river.250 ·
Day 3 isn’t automatically abnormal—what dose and titration schedule are you on?
gamer943 @gamer943 ·
Day 3 doesn’t automatically make it “normal”—semaglutide nausea can persist, but severity matters. If you can’t keep fluids down, contact your prescriber promptly.
danbear @danbear ·
Day 3 is rough. Nausea can linger early with semaglutide; if you can’t keep fluids down, contact your prescriber.
stickshift @stickshift ·
GI effects vary; day 3 isn’t definitive.
justnorthshore @justnorthshore ·
day 3 for you too?